A Drug A Day

careful, you'll get addicted


Hydrocortamate is a drug applied topically for relief from inflammation as a result of corticosteroid-responsive dermatoses. Hydrocortamate is a synthetic glucocorticoid with immunosuppressive and anti-inflammatory properties.



Desvenlafaxine is a serotonin norepinephrine reuptake inhibitor, an antidepressant.The drug is a synthetic form of the main major metabolite of venlafaxine, and is currently being used as the first non-hormone based treatment for alleviation of menopause symptoms. The primary use of the drug is to treat major depressive disorder.

Desvenlafaxine works by blocking the reuptake transporters for the key neurotransmitters affecting mood, and so more active neurotransmitters are left in the synapse.

Common adverse effects include nausea, hyperhidrosis, diarrhoea, dry mouth and fatigue.


Acrivastine is a drug used in the treatment of allergies. The drug is a second generation H1 receptor antagonist antihistamine and works by blocking histamine H1 receptors.

The drug is a non-sedating antihistamine and can be taken up to three times a day, in contrast with other antihistamines such as cetirizine.


Acebutolol is a medication used to treat hypertension and cardiac arrhythmias. Acebutolol is a cardio selective beta blocker with intrinsic sympathomimetic activity, and so is infinitely more suitable than non-cardioselective beta blockers for patients with chronic obstructive pulmonary disease or asthma due to the fact that doses lower than 800mg daily have only 10-30% of the constricting effects on the bronchial system that treatments such as propanolol may have.

Acebutolol is also recommended over other beta blockers due to the lack of impact on the serum lipids; cholesterol and triglycerides.

A common side effect (10-30% of patients) includes the development of anti nuclear antibodies.



Short one today, as I’m studying for exams!

Amitriptyline is a medication used to treat a variety of mental illnesses, treatment of neuropathic pain and for the prevention of migraines.

Amitriptyline is a tricyclic antidepressant, but the exact nature of the mechanism is unclear. Common side effects of taking amitriptyline include low blood pressure, dry mouth, vision impairment, constipation and sleepiness. Glaucoma, increased risk f suicide in under 25’s, urinary retention and cardiovascular issues.



Prednisolone is a type of steroid medication that is used to treat allergies, cancers, inflammatory conditions and autoimmune disorders. The drug can be administered by injection, as eye drops, as a topical cream or by mouth.

Prednisolone is a glucocorticoid derived from hydrocortisone. Corticosteroids work by inhibiting the inflammatory response to a variety of agents. The lipophilic structure of prednisolone helps with the easy passage of the drug through the cell membrane, where it binds to the respective glucocorticoid receptor in the cytoplasm. After binding, the GC/GCR abuses a dissociation of the chaperone proteins from the glucocorticoid receptor, enabling the translocation of the complex inside the nucleus. The GC/GCR complex binds to glucocorticoid response elements, which then results in gene inhibition/expression. Synthesis of anti-inflammatory proteins occurs by complex binding to positive glucocorticoid response elements, whereas negative glucocorticoid response elements block the transcriptions of inflammatory genes.




Anti-thyroid drugs are a type of drugs used to control thyrotoxicosis. Thioamides work by inhibiting the enzyme thyroid peroxidase in the blood, and so the synthesis of thyroxine and triiodothyronine is then reduced. This blocks the uptake of iodotyrosines from the colloid.

Common adverse effects include dermatitis, urticaria, skin eruptions and arthralgia. Due to the ability of thioamides to cross the placental barrier, caution is advised for use during pregnancy.


Docusate is a laxative that can Ben used to treat constipation, and is particularly appropriate for use for children with hard faeces for relief.

Docusate works through softening the stools by allowing more water to be absorbed into the faeces. Docusate can be used to alleviate constipation caused by use of opiates, in conjunction with an active stimulant laxative.

Azelaic Acid

Azelaic acid is a dicarboxylic acid type medication. Mostly used for dermatological conditions such as mild to moderate (comedonal and inflammatory) acne, rosacea, melasma, through different mechanisms of function.

Azelaic acid kills the acne-causing bacteria in the pores of the skin, also decreasing the production of keratin which can promote acne bacteria growth. By inhibiting the conversion of cathelicidin into the anti microbial skin peptide LL37,  it can also be used as a topical treatment for rosacea.

Powered by

Up ↑