Methylphenidate is a psychostimulant commonly prescribed for treatment of ADHD and similar conditions.  The drug works by increasing the activity of the central nervous system, combating fatigue, improving attention and maintaining alertness.

Methylphenidate works by inhibiting catecholamine reuptake by acting as a dopamine reuptake inhibitor, blocking the dopamine transporter and norepinephrine transporter. This leads to increased concentrations of norepinephrine and dopamine within the synaptic cleft, leading to the increased neurotransmission of both.